The CENC is dedicated to establishing a comprehensive understanding of the chronic effects associated with neurotrauma, primarily focused on mTBI/concussion. Briefly, the DoD/VA defines mTBI as associated with normal structural imaging (excluding DTI, fMRI, etc.), loss of consciousness lasting 30 minutes or less, alteration of consciousness/mental state from a moment up to 24 hours, and post-traumatic amnesia lasting 1 day or less.
A key priority of the CENC is the development of diagnostics, including a broad range of biomarkers, and novel treatment and rehabilitative strategies to improve the long-term health and well-being of Service members and Veterans. The CENC coordinates research activities, including translational, preclinical and clinical studies, and the collection, storage, use, and analysis of data and anatomical specimens, with an emphasis on basic and preclinical studies to address issues regarding anatomic, molecular, and physiological disease mechanisms issues and a heavy emphasis on clinical studies to address issues regarding comorbidities issues.
The CENC provides critical information to benefit Service members and Veterans by enhancing diagnosis, treatment, and rehabilitation strategies.