Publications

Preface: Chronic effects of neurotrauma consortium

PTSD confounds detection of compromised cerebral white matter integrity in military veterans reporting a history of mild traumatic brain injury

Vestibular, balance, microvascular and white matter neuroimaging characteristics of blast injuries and mild traumatic brain injury: Four case reports

Advanced neuroimaging to quantify myelin in vivo: Application to mild TBI

Active duty service members who sustain a traumatic brain injury have chronically elevated peripheral concentrations of Aβ40 and lower ratios of Aβ42/40

Chronic cerebrovascular abnormalities in a mouse model of repetitive mild traumatic brain injury

Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study

A retrospective cohort study of comorbidity trajectories associated with traumatic brain injury in veterans of the Iraq and Afghanistan wars

Supervised learning technique for the automated identification of white matter hyperintensities in traumatic brain injury

Inflammatory changes in optic nerve after closedhead repeated traumatic brain injury: Preliminary study

The Chronic Effects of Neurotrauma Consortium (CENC) multi-centre observational study: Description of study and characteristics of early participants

Quantitative structural neuroimaging of mild traumatic brain injury in the Chronic Effects of Neurotrauma Consortium (CENC): Comparison of volumetric data within and across scanners

MacDonald C, Johnson A, Douay B, Evans N, Helmer P, Sullivan B, Tong M, Winters A, Dikmen S. (2016). Preliminary Comparison of 1 and 5 year follow up in Active Duty Blast TBI and Combat Controls - Evolution Not Resolution of Symptoms. Presented at the Military Health System Research Symposium.

Mufson EJ, Perez SE, Lee SH, Petkova E, McKee AC, Ginsberg SD. (2016). Preliminary expression profiling of tau-positive cholinergic basal forebrain neurons in the nucleus basalis of Meynert in postmortem chronic traumatic encephalopathy brain: A Chronic Effects of Neurotrauma Consortium Study.

Cifu DX: CENC: Shedding new light on Combat-associated Concussions (Lecture) International Society of Physical and Rehabilitation Medicine World Congress, Kuala Lumpur, Malaysia, June 1, 2016.

Cifu DX: CENC Update: Year 2 (Lecture) International Brain Injury Association World Congress, The Hague, Netherlands, March 5, 2016

Cifu DX: Management of Peristent Symptoms after Concussion (Lecture) Philippines Assocation of Physical & Rehabilitation Medicine (PARM) Annual Meeting, Manila, Philippines, February 17, 2016.

Cifu DX: Overview of Aquatic Rehabilitation (Lecture) Philippines Assocation of Physical & Rehabilitation Medicine (PARM) Annual Meeting, Manila, Philippines, February 17, 2016.

Cifu DX: Management of Common Complications and Conditions After TBI (Lecture) Philippines Assocation of Physical & Rehabilitation Medicine (PARM) Annual Meeting, Manila, Philippines, February 17, 2016.

Cifu DX: Managing Conditions and Complications after Traumatic Brain Injury (Lecture) The 3rd Regional Scientific Meeting of International Society of Physical & Rehabilitation Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabi, February 7, 2016

Cifu DX: Acute and Longterm Management of Concussion (Lecture) The 3rd Regional Scientific Meeting of International Society of Physical & Rehabilitation Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabi, February 9, 2016

Bowser, R.: Mechanisms of cognitive impairment in ALS patients, genetic causes, mutations in TDP-43 and the RNA-binding protein FUS (Fused in Sarcoma/Translocated in Sarcoma). Winter Conference on Neural Plasticity, Maui, HI, January 30 - February 6, 2016.

Mufson, E.: Chronic traumatic encephalopathy (CTE) as a tauopathy. Winter Conference on Neural Plasticity, Maui, HI, January 30 - February 6, 2016.

Perl, D.: Transactive response (TAR) RNA/DNA binding protein TDP-43 and its involvement in neurodegenerative diseases (Lecture). Winter Conference on Neural Plasticity, Maui, HI, January 30 - February 6, 2016.

Cifu DX: Update on the Chronic Effects of Neurotrauma Consortium (Lecture) Grand Rounds, Prince Sultan Military Medical City, Riyadh, Saudi Arabi, November 7, 2015

Cifu DX: Battlefield to Ballfield: Concussion Update (Lecture), University of Missouri Department of PM&R, Columbia, MO, October 23, 2015.

Cifu DX: Battlefield to Ballfield: Mild TBI Update (Keynote Address), National Conference of Rehabilitation Educators, Bethesda, MD, October 20, 2015.

Cifu, D.X.: The VA/DoD Chronic Effects of Neurotrauma Consortium: An Overview at Year 1. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL, August, 2015.

West, S.L., & Cifu, D.X.: Understanding the long-term consequences of mild traumatic brain injury in active duty service members. Presented to MILHEALTH 2015, Washington, DC., July 2015

Cifu D.X.: Battlefield to Ballfield: Mild TBI Update (Keynote Lecture), John A Burns School of Medicine Conference, Honolulu, HI, June 10, 2015.

Cifu D.X.: TBI Collaborative Research (Panel Discussant), One Mind Annual Meeting, Crystal City, VA, May 27-28, 2015.

Cifu D.X.: Battlefield to Ballfield: Mild TBI Update (Keynote Lecture), Colorado Brain Injury Consortium Conference, Grand Junction, CO, May 7-8, 2015.

Cifu D.X.: TBI-CENC Research Update (Lecture), Arrowhead TBI Conference, Washington DC, April 15-16, 2015

Cifu D.X.: TBI-CENC Research Update (Lecture), CAVRN Annual Meeting, San Diego, California, March 9-11, 2015.

Cifu D.X.: TBI Research Update (Lecture) 5th Annual Comprehensive Advanced Restorative Effort conference, San Diego, California, December 5-7, 2014.

Cifu D.X.: TBI Rehabilitation Update (Keynote Address) Asian Prosthetic and Orthotic Scientific Meeting/International Society of Neurorehabilitation Meeting, Taipei, Taiwan, November 29-30, 2014

Cifu D.X.: VA Polytrauma System of Care (Keynote Address) International Trauma Conference, Seoul Korea, November 21, 2014.

Cifu D.X.: Evidence Based Approach to mTBI Management (Keynore Lecture), New Hampshire Medical Society Annual Scientific Meeting, Meredith, NH, November 7, 2014.

Cifu D.X.: Chronic Effects of Neurotrauma Consortium (Lecture) Strong Star PTSD Conference, San Antonio, Tx, October 21-22, 2014.

Cifu D.X.: From Battlefield to Ball Field: The Myth, Science and Reality of Concussions (Grand Rounds) VCU Department of Internal Medicine, Richmond, VA, October 9, 2014.

Cifu D.X.: From Battlefield to Ball Field: The Myth, Science and Reality of Concussions (Grand Rounds) VCU Department of PM&R, Richmond, VA, October 3, 2014.

Cifu D.X.: Sport-specific Assessment and Management of Vestibular and Concussive Dysfunction (Invited Course: Professional Hocket Athletic Trainers Society/Society of Professional Hockey Equipment Managers Society annual meeting) Orlando, Florida, June 23, 2014.

Cifu D.X.: Concussion Diagnosis and Management: Playing Field to Battlefield (Keynote Lecture Rehabilitation Insitute of Chicago TBI Conference) Chicago, Illinois, June 5, 2014.

Cifu D.X.: Managing Post-Deployment Syndrome (University of Montana Invited Lecture) Missoula, Montana, May 22, 2014

Cifu D.X.: Concussions from the Playing Field to the Battlefield (VCU: Rao R. Ivatury Trauma Symposium) Richmond, Virginia, April 30, 2014

Cifu D.X.: Rehabilitation of Combat Associated Polytrauma (Annual PM&R Conference) Singapore, March 27, 2014.

Cifu D.X.: Vestibular Dysfunction After Concussion (University of Utah Department of PM&R: Annual Update in PM&R) Park City, Utah, January 31, 2014.

Cifu D.X.: VHA's Polytrauma System of Care 2013 (Advances in VHA Care) Richmond VA, October 28, 2013.

Cifu D.X.: Chronic Effects of Neurotrauma Consortium: Update (VCU Department of Anatomy Grand Rounds) Richmond, VA, October 25, 2013

West, S.L. & Cifu, D.X. (October, 2014). The Chronic Effects of Neurotrauma Consortium: Studying the Future Effects of Combat-Related Brain Injury Today. Paper presented at the Australasian Military Medicine Association Annual Conference, Sydney, Australia.

Byers A, Li Y, Barnes D, Seal K, Boscardin J, Yaffe K. (2016). Traumatic Brain Injury and risk of mortality in late life. Presented at the Gerontological Society of America Annual Meeting.

Gardner RC, Byers A, Barnes DE, Li Y, Boscardin J, Yaffe K. (2017). Mild Traumatic Brain Injury is associated with increased risk of Parkinson Disease in military veterans: a Chronic Effects of Neurotrauma Consortium Study. Presented at the American Academy of Neurology Annual Meeting.

Lin X, Liu Q, Vogt GS, Diaz MA, Mayer AR, Taylor B, Wilde EA, Garza H, Steinberg JL, Troyanskaya M, Vasquez AC, Cadrain R, Jak A, Bangen KJ, Levin HS, Walker WC, Scheibel RS, Newsome MR. (2016). Determining a threshold for correcting for motion artifact in functional neuroimaging data in Veterans with mild Traumatic Brain Injury. Presented at the Mission Connect 2016 Annual Scientific Symposium in Houston, TX.

Lin X, Liu Q, Vogt GS, Diaz MA, Mayer AR, Taylor B, Wilde EA, Garza H, Steinberg JL, Troyanskaya M, Vasquez AC, Cadrain R, Jak A, Bangen KJ, Levin HS, Walker WC, Scheibel RS, Newsome MR. (2016). Determining a threshold for correcting for motion artifact in functional neuroimaging data in Veterans with mild Traumatic Brain Injury. Presented at the Second Annual Michael E. DeBakey VA Research Symposium.

Miskey HM, Martindale SL, Shura RD, Taber KH. (2017). Distress tolerance and symptom severity mediate failure on a symptom validity test in Iraq and Afghanistan Veterans with PTSD. Presented at the American Neuropsychiatric Association Annual Meeting.

Perez SE, He B, McKee AC, Lee SH, Petkova E, Chao HM, Ginsberg SD, Mufson EJ. (2017). Expression profiling of tau-positive cholinergic neurons within the nucleus basalis of Meynert in brains from veterans and athletes with a postmortem diagnosis of chronic traumatic encephalopathy (CTE): A Chronic Effects of Neurotrauma Consortium Study. Presented at the International Brain Injury Conference.

Shura RD, Martindale SL, Brearly TW, Rowland JA, Taber KH. (2017). Intelligence and possible Attention-Deficit/Hyperactivity Disorder (ADHD) as risk factors for Posttraumatic Stress Disorder (PTSD) in Veterans. Presented at the American Neuropsychiatric Association Annual Meeting.

Olivera A, Lejbman N, Jeromin A, French LM, Kim HS, Cashion A, Mysliwiec V, Diaz-Arrastia R, Gill J. (2015). Peripheral Total Tau in Military Personnel Who Sustain Traumatic Brain Injuries During Deployment. Presented at the Military Health System Research Symposium.

Kenney K, Diaz-Arrastia R, McKee A, Perl D. (2016). Latent Dementia after Single Moderate/Severe TBI: The Clinicopathological Findings in 2 Cases. Presented at the Military Health System Research Symposium.

Barnes DE, Byers AL, Seal K, Boscardin WJ, Yaffe K, and the Chronic Effects of Neurotrauma Consortium Study Group. (2016). Mild Traumatic Brain Injury and Risk of Dementia in Veterans. Presented at the Alzheimer's Association International Conference.

Byers AL, Li Y, Barnes DE, Boscardin WJ, Seal K, Yaffe K, and the Chronic Effects of Neurotrauma Consortium Study Group. (2016). Mild Traumatic Brain Injury and Risk of Mortality in Late Life. Submitted to Gerontological Society of America National Conference.

Seal KH, Bertenthal D, Barnes DE, Byers AL, Boscardin WJ, Yaffe K, and the Chronic Effects of Neurotrauma Consortium Study Group. (2016). Association of Traumatic Brain Injury with Chronic Pain in Iraq and Afghanistan Veterans: Additive Effects of Comorbid Mental Health Conditions and Implications for Treatment. Presented as an oral presentation at the Military Health System Research Symposium.

Barnes D, Byers A, Boscardin J, Seal K, Yaffe K. (2015) Agent Orange Exposure and Risk of Dementia in Vietnam Veterans (abstract) Presented at the Alzheimer's Association International Conference.

Dixon K & Randhi R. Soluble TNF blocker alleviates TNFR1-mediated pain following TBI. (2016). Presented at NCA TBI Research Symposium.

Swan AA, Nelson JT, Swiger BS, Jaramillo CA, Eapen BC, & Pugh MJ. (2016). A Chronic Effects of Neurotrauma Consortium investigation of hearing loss and tinnitus: prevalence and comorbidities associated with traumatic brain injury in Iraq and Afghanistan veterans. Presented at San Antonio SURF and MHSRS.

Pugh MJ, Amuan M, Van Cott AC, Baca C, Parko K. (2016). Mortality in Post-9/11 veterans with epilepsy: a Chronic Effects of Neurotrauma Consortium Study. Presented at AMSUS and American Epilepsy Society.

Mufson EJ, Perez SE, McKee AC, Ginsberg S. Gene dysregulation in tau positive cholinergic basal forebrain neurons post chronic traumatic encephalopathy: Preliminary observations. Presented at NS meeting.

Barnes DE, Byers AL, Seal K, Boscardin WJ, Yaffe K, and the Chronic Effects of Neurotrauma Consortium Study Group. (2016). Mild Traumatic Brain Injury and Risk of Dementia in Veterans. Presented at Alzheimers Association International Conference.

Morin A, Ojo JO, Crynen G, Ait-Ghezala G, Mouzon B, Ferguson S, Crawford F. (2016) Epigenomic approach to therapeutic target identification, validation and drug discovery for traumatic brain injury. Presented at NS meeting.

Morin A, Mouzon B, Ferguson S, Crawford F. (2016) Dihydrophiridine calcium channel antagonist (Nilvadipine) is potential drug against repetitive mild TBI. Presented at Society for Neuroscience Meeting.

Bachmeier C, Ojo J, Shackleton B, Lynch C, Mouzon B, Crawford F. (2016). Role of cerebrovascular cells in tau processing following traumatic brain injury. Presented at International Neurotrauma Society Symposium.

Ojo J, Algamal M, Diamond D, Mullan M, Crawford F. (2016). Modeling PTSD and repetitive concussive injury (from mice to men). Presented at the International Neurotrauma Society Symposium.

Ojo J, Reed J, Ajoy R, Algamal M, Mullan M, Crawford F. (2016). Exploring the molecular overlap in the brain and plasma of repetitive mTBI and ad mouse models using proteomics technology. Presented at the International Neurotrauma Society Symposium.

Crawford F, Bachmeier C, Mouzon B, Ojo J, Lynch C, Ferguson S, Mullan M. (2016). Influence of a Western diet and APOE genotype on outcome after mild repetitive TBI in a mouse model. Presented at the International Neurotrauma Society Symposium.

Mouzon B, Ojo J, Bachmeier C, Algamal M, Leary P, Lynch C, Paris D, Mullan M, Crawford F. (2016). Life-long sports-related repetitive concussive head injury in HTAU mice: Deficits in cerebral blood flow, gliosis, axonal injury, and mild increase(s) in t-tau and tau oligomers. Presented at the International Neurotrauma Society Symposium.

Belanger, H., Silva, M. A., McKenzie-Hartman, T.,   Vanderploeg, R. D. (2015). Is the Neurobehavioral Symptom Inventory (NSI) A Good Outcome Measure? A Chronic Effects of Neurotrauma (CENC) and VA TBI Model System Study. Presented at the Military Health System Research Symposium.

Belanger, H.,   Vanderploeg, R. D. (2015). Mass TBI Screening in VHA: Is There Evidence? Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Bieler, G. S., Egglston, B., Nolen, T., Temkin, N., & Williams, R. L. (2015). Predictive modeling approaches for predicting cognitive impairment in veterans and service members with a history of mild traumatic brain injury using longitudinal, observational data. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Emmerich, T., Abdullah, L., Crynen, G., Dretsch, M., Evans, J., Ait-Ghezala, G., ... Crawford, F. (2015). Translational plasma lipidomic profiling in military populations with TBI, PTSD and TBI+PTSD and correlation to mouse models of these conditions. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Ferguson, S., Mouzon, B., Paris, D., Abdullah, L., Aponte, D., Crynen, G., ... Crawford, F. (2015). Screening potential TBI therapeutics in a Pre-Clinical Model of Repetitive mild TBI. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Gilmore, C. S., Camchong, J., Sponheim, S. R., Kardon, R. H.,   Lim, K. O. (n.d.). Deficits in Visual System Functional Connectivity after Blast-Related Mild TBI are Associated with Injury Severity and Executive Dysfunction. In 2015. Fort Lauderdale, FL.

Hall, C., Akin, F.,   Murnane, O. (2015). Otolith Dysfunction and Postural Stability. Presented at the Military Health system Research Symposium, Fort Lauderdale, FL.

Haskin, A. C., Dillahunt-Aspillaga, C., Silva, M. a., Schmitt, M., Pugh, M. J., McGarity, S.,   Nakase-Richardson. (2015). Injury and Psychological Predictors of Employment Stability in Veterans and Service Members with TBI: A VA Brain Injury Model Systems Study. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Mac Donald, C. (2015). The ADAPT Study. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

McKenzie-Hartman, T., Silva, M.,   Nakase-Richardson, R. (2015). Neuropsychological Testing is predictive of severity of disability following Traumatic Brain Injury: Findings from the VA TBI Model Systems   Implications for the Chronic Effects of Neurotrauma Consortium. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Mouzon, B., Bachmeier, C., Olubunmi, J., Ferguson, S., Lynch, C.,   Crawford, F. (2015a). The Role of Tau and Other Pathologies in an Animal Model of Repetitive Mild Traumatic Brain Injury. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Nakase-Richardson, R., Lamberty, G., Silva, M. A., Pugh, M. J., Haskin, A. C., Ropacki, S., ... Cifu, D. X. (2015). Feasibility of Enrollment and Tracking of Longitudinal Outcomes Following TBI: A VA TBI Model System Study. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Ojo, J., Algamal, M., Reed, J., Mouzon, B., Mullan, M., Diamond, D.,   Crawford, F. (2015). Modeling PTSD and repetitive concussive injury in animal models. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Silva, M. A., Martinez, K. M., Schmitt, M., Lynn, C. A., Dillahunt-Aspillaga, C., Garofano, J. S.,   Nakase-Richardson, R. (n.d.). Demographic, Mental Health, and Functional Characteristics of Active Duty Service Members and Veterans Returning to School after Inpatient TBI Rehabilitation: A VA TBI Model System Study. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Theriaque, D. W., Wilson, K. A., Matthews, D. A., & Siege, C. (2015). Informatics Best-practices to Facilitate Data Sharing Using the Federal Interagency TBI Research (FITBIR) Informatics System. Presented at the Military Health Systems Research Symposium, Fort Lauderdale, FL.

Tran, J., Scott, S., McCarthy, M., Eapen, B., Schmitt, M.,   Nakase-Richardson, R. (n.d.). Deployment-related rehospitalizations following TBI: A VA TBI Model Systems Study. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Tzekov, R., Orlando, M., Dawson, C., Mouzon, B., Murdocca, P., Lynch, C.,   Crawford, F. (2015). Morphological and immunohistochemical characteristics of optic nerve damage post repeated traumatic brain injury. Presented at the Military Health System Research Symposium, Fort Lauderdale, FL.

Farrell, E. K., Nadeem, M., Perez, S. E., Crawford, F., Stein, T., Alvarez, V., ... Mufson, E. J. (2015). Tau pathology within the nucleus basalis of Meynert in athletes with traumatic brain injury. Presented at the Military and Veterans Health After a Decade at War: Lessons Learned and the Road Ahead, Washington, D.C.

Copeland, L. A., Bollinger, M., Finley, E. P., Amuan, M., Pugh, J., & Pugh, M. J. (2015). Five-Year Mortality Correlates for Veterans of Iraq and Afghanistan. Presented at the VA Health Services Research and Development Service National Meeting, Philadelphia, PA.

Pugh, M. J., & Jaramillo, C. J. (2015). Risk Factors for Headache and Persistent Headache in an Inception Cohort of Iraq and Afghanistan War Veterans. Presented at the VA Health Services Research and Development Service National Meeting, Philadelphia, PA.

Pugh, M. J., Jaramillo, C. J., Finley, E. P., Copeland, L. A., Van Cott, A., Mortensen, E., ... Pugh, J. (2015). Stability of Health Trajectories Among Iraq and Afghanistan Veterans: Insights from Central Nervous Sytem Medication Use. Presented at the VA Health Services Research and Development Service National Meeting, Philadelphia, PA.

Song, K., Collett, G., Jaramillo, C., Potter, J., Finley, E. P., & Pugh. (2015). The Burden of Central Nervous System Polypharmacy in Iraq and Afghanistan Veterans: Prevalence and Associated Risks. Presented at the VA Health Services Research and Development Service National Meeting, Philadelphia, PA.

Swan, A., Jaramillo, C., Eapen, B., & Pugh, M. J. (2015). Tinnitus: Prevalence and Comorbidities in a Cohort of Iraq and Afghanistan Veterans. Presented at the VA Health Services Research and Development Service National Meeting, Philadelphia, PA.

Algamal, M., Ojo, J. O., Reed, J. M., Abdullah, L., Crynen, G., Leary, P., ... Crawford, F. (2015). Exploring the molecular overlap in the brain and plasma of TBI and AD mouse models using proteomic and lipidomic technology. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Crawford, F., Bachmeier, C., Abdullah, L., Reed, J., Lynch, C., Evans, J., ... Mullan, M. (2015). The effects of APOE genotype on proteomic and lipidomic response to injury in different mouse models of TBI. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Ferguson, S., Mouzon, B., Aponte, D., Crynen, G., Mathura, V., Mullan, M.,   Crawford, F. (2015). Visual dysfunction screening in mice after TBI using an optomotor assessment of the optokinetic response. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Lynch, C., Bachmeier, C., Mouzon, B.,   Crawford, F. (2015). Chronic Impairment of Cerebral Blood Flow in a Mouse Model of Repetitive Mild Traumatic Brain Injury. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Mouzon, B., Bachmeier, C., Olubunmi, J., Ferguson, S., Lynch, C.,   Crawford, F. (2015b). The role of tau and other pathologies in an animal model of repetitive mild traumatic brain injury. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Ojo, J. O., Mouzon, B., Bachmeier, C., Algamal, M., Leary, P., Pelot, R., ... Crawford, F. (2015). Exploring different pathological biomarkers in the grey and white matter of a newly developed model of chronic repetitive concussive head injury. Presented at the National Neurotrauma Symposium, Santa Fe, NM.

Cifu, D.X. (2015) VCU Researcher Pleased with Film’s Focus on Concussions All Things Considered, WCVE/NPR with John Ogle. Aired November 13, 2015.

Kruszewski, J. (2015). Richmond Professors Use Bio-Math to Help Soldiers With Brain Injuries Style Weekly November 10, 2015


Issue 1; Winter 2016